CGF-PRP
What is CGF-PRP?
It is a method of healing damaged tissues using the patient’s own blood. The main elements of blood that provide healing in tissue damage are platelets (blood platelets) and growth factors released from them.
This mechanism of healing may be insufficient in some tissue damages and chronic diseases occur. For example, this is the case in chronic herniated discs, nerve damages, and joint calcifications. In these cases, platelets, growth factors and stem cells (CD34) found in small amounts in the blood can be concentrated and given to damaged tissues to provide healing.
PRP (Platelet Rich Plasma)
It means Platelet Rich Plasma. Its healing effect depends on the growth factors in platelets. In order to be effective in tissue damages, it must be activated by some methods and the growth factors must be released. PRP administered without activation has no healing effect on damaged tissues.
CGF (Concentrated Growth Factor)
It means concentrated growth factors. When given to tissues, it has a direct healing effect. Also, when given directly from the blood, it ensures that the stem cells in circulation are more than normal for a week.
Stem Cell (CD34)
There are very few stem cells in the bloodstream. The characteristic of stem cells is that they directly transform into tissue cells in the tissue they are given to. In this way, it ensures the healing of tissues that normally have no chance of healing, such as cartilage cells and nerve cells.
How is it Obtained?
20-80 cc of blood is taken depending on the width of the damaged tissue. It is centrifuged in special tubes at certain speeds and for certain periods. At the end of the process, PPP (Platelet Poor Plasma), PRP (Platelet Rich Plasma), CGF (Concentrated Growth Factor), CD34 (Stem Cell) and erythrocyte layers are formed in the tubes. All of these layers, except the erythrocyte layer, are collected in separate injectors and used for treatment after being ozonated for activation.
How is the application done?
Half of the serums containing CGF and CD34 are given to the damaged tissue, and the remaining half is given directly to the blood through a vein. The part given to the damaged tissue both contributes to tissue healing and ensures that all stem cells in circulation and other blood cells involved in healing migrate to the damaged tissue by marking the damaged tissue. Thus, the entire healing potential of the body is activated for the damaged tissue. PRP and PPP serums are activated with ozone and then given to the surroundings of the damaged tissue to maintain healing.
In Which Diseases is it Applied?
- Waist-neck: Hernias, nerve compression
- Knee: Calcifications in the knee, ligament and meniscus tears, cartilage injuries, tendon inflammations
- Shoulder: Tendon inflammations frequently seen in the shoulder, sequelae due to traumatic injuries, joint arthritis
- Elbow-hand: Tennis and golfer’s elbow, tendon inflammations
- Foot: Heel spurs, tendon inflammations
- Unhealed wound treatments
How Many Sessions Are Applied?
Depending on the condition of the disease, 1-4 injections applied at 2-3 month intervals are sufficient.
Does It Have Any Side Effects?
Since it is prepared from the person’s own blood, it has no serious side effects other than mild pain after the injection if sterility conditions are followed. If there is pain after the application, ice application and paracetamol-type painkillers can be used. Non-steroid anti-inflammatory drugs (such as voltaren, naproxen, majezik) are not recommended as they will reduce the effectiveness of the application. Strenuous exercise and sports are not recommended after the application. Simple stretching exercises can be done, but heavy resistance weight training should be avoided. Bandages may be applied.
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